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Why flu season happens and how to help protect yourself
Learn why flu season peaks in colder months, who’s most at risk, and why getting a yearly flu shot is important to help protect yourself.
6 min read
Key takeaways
What is flu season, and why does it matter?
Every year, as the weather cools and people spend more time indoors, flu season begins. But what exactly is flu season, and why does it come back every year?
Influenza, or the flu, is a contagious respiratory illness caused by influenza viruses. It can lead to mild to severe illness and, in some cases, serious complications including death. People can have fever, cough, sore throat, body aches, and fatigue. People can be contagious (i.e., transmit the flu virus to others) even before they know they are sick. While most people recover on their own within a week, but the flu can be dangerous—especially for children under five, older adults, and people with certain health conditions.
Understanding flu season can help you take timely steps to help protect yourself and those around you.
When is flu season?
In the Northern Hemisphere, including the United States, flu season typically begins in October, peaks between December and February, and lasts through April. However, the exact timing can vary by region and year.
In the Southern Hemisphere, flu season usually occurs from April to September, aligning with their winter months. In tropical regions, flu activity can occur year-round but may still have seasonal peaks.
Why do we have a flu season?
Several factors contribute to the seasonal nature of the flu:
- Colder weather: Flu viruses survive and spread more easily in cold, dry air.
- Indoor crowding: People spend more time indoors during colder months, increasing close contact and the chance of transmission.
- School sessions: Schools are crowded with both children and adults, who are at risk for the flu, and flu season typically coincides with the school year.
- Holidays: During holidays such as Thanksgiving, Christmas and New Years people often travel, have family get-togethers, and attend religious events, which can increase the risk of getting the flu from others.
- Weakened immune systems: Less sunlight in the winter can contribute to lower levels of vitamin D, which may affect immune function.
Are some flu strains worse than others?
Yes. Influenza viruses are constantly changing. Each year, different strains circulate—some more severe than others. The flu vaccine is updated annually to target the strains expected to be most common.
Some years, the dominant strain may cause more severe illness or spread more easily, which can lead to a more intense flu season.
Who gets the flu?
Anyone can catch the flu, but some groups are more vulnerable to complications:
- Adults 65 and older
- Young children, especially under the age of 5
- Pregnant women
- People with certain chronic conditions, such as asthma, diabetes, or heart disease
- People with weakened immune systems
How to protect yourself from the flu
The best way to help protect yourself and others is to take preventive steps:
- Get vaccinated every year if older than 6 months of age.
- Wash your hands frequently with soap and water or use a waterless alcohol-based hand hygiene product.
- Avoid close contact with people who are sick.
- Stay home if you’re feeling unwell.
- Cover your coughs and sneezes with a tissue or your elbow, dispose of the tissue and then perform hand hygiene.
If you are at high risk for serious disease (e.g., you are being treated for cancer and immunocompromised), consider wearing a mask outside your home or when inside and in close proximity to other people.
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types
Most flu vaccines protect against three or four types of influenza viruses: two influenza A viruses (H1N1 and H3N2) and one or two influenza B viruses (from the B/Yamagata or B/Victoria lineages).
The flu vaccine: what you need to know
The flu vaccine can help protect against seasonal influenza. The flu vaccine helps lower the chances of getting sick and reduces the risk of severe complications that could lead to hospitalization. Designed to help your immune system recognize and fight off the most likely strains of the virus each year, the vaccine is available as a shot or nasal spray. Flu vaccination is recommended for everyone age six months and older.
- Timing matters: the US Centers for Disease Control and Prevention suggests getting vaccinated by the end of October, before flu activity typically peaks. However, it’s still beneficial to get a flu shot later in the season if you miss that window.
- Co-administration: If you’re eligible, you may be able to get the flu vaccine along with another vaccine in the same visit. Read more about getting more than one vaccine.
- Reformulated annually: Because flu viruses constantly evolve, the vaccine is changed annually. Each year, researchers analyze data from around the world to predict which strains are most likely to circulate. Based on this data, the vaccine is updated to include protection against the most prevalent strains. Most flu vaccines help protect against three types of influenza viruses: two influenza A viruses (H1N1 and H3N2) and one influenza B virus. This is why getting vaccinated every year can be beneficial. Importantly, more than 1 type of flu virus spreads each year, thus unvaccinated people can get the flu more than once in a single respiratory viral season.
Special Considerations
Some people may need special considerations:
- Older adults and adults with a solid organ transplant (e.g., kidney) (especially those 65 years and older) may benefit from high-dose or adjuvanted versions, which include an added ingredient to help strengthen the body’s immune response. The US Centers for Disease Control and Prevention specifically recommends one of these “enhanced” vaccines for older people and adults who have had a transplant.
- Pregnant individuals are encouraged to get vaccinated to help protect themselves and their unborn child. Pregnant women should discuss with their healthcare provider about receiving the flu vaccine earlier in the Fall.
- People with a weakened immune system should receive inactivated flu vaccines. Live attenuated vaccines (like the nasal spray) are generally not recommended.
- People with egg allergies can opt for egg-free formulations but the Centers for Disease Control and Prevention states that such people may receive any age-appropriate flu vaccine.
It’s also important to note that many people use the term “flu” to describe any respiratory illness during the winter months. However, the flu vaccine only protects against influenza viruses. While there are vaccines for other respiratory viruses—like COVID-19 and RSV—not all respiratory illnesses are preventable by vaccination, including rhinovirus (common cold) and human parainfluenza viruses (HPIV).
Stay ahead of the flu
Flu season may come around every year, but that doesn’t mean you have to face it unprepared. By understanding how and when the flu spreads—and taking simple steps like getting vaccinated every year—you can help protect yourself. Visit VaxAssist.com to check your eligibility for respiratory vaccines, schedule your flu vaccine appointment and learn more.
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Frequently
asked questions
Can you get the flu from the flu vaccine?
No. The flu shot contains inactivated virus or no virus at all. The flu nasal spray contains live attenuated virus. Neither option can cause the flu.
Can I get vaccinated while sick?
Talk to your healthcare provider or pharmacist, but typically if you have a mild illness (like a cold), it’s usually fine to get a flu vaccine.
Is the flu shot effective every year?
Effectiveness varies depending on how well the vaccine matches circulating strains, but it still reduces the risk of severe illness and hospitalization. If you do get the flu, antiviral medications are available. These are most effective when started within two days of symptom onset and are especially important for older adults and people with certain underlying heath conditions.
What is the flu season timeline for 2025–2026?
Flu season in the U.S. is expected to start in October 2025, peak in January or February 2026, and taper off by May 2026.
What strains are included in the 2025–2026 flu vaccine?
Each year’s vaccine includes 3 strains based on global data.
Where can I get vaccinated?
Flu shots are available at pharmacies, clinics, medical offices, and some workplaces. Use VaxAssist by Pfizer to check your eligibility and locate a site near you.
Is the flu vaccine free?
Costs vary based on insurance coverage, but most plans cover the flu vaccine at no cost. Many public health clinics also offer free or low-cost options.
Why get vaccinated every year?
Because flu viruses change and immunity fades, annual vaccination is a great way to help stay protected.
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References
5 myths about the flu vaccine. The World Health Organization. Accessed July 7, 2025. https://www.who.int/news-room/spotlight/influenza-are-we-ready/5-myths-about-the-flu-vaccine
About Influenza. The Centers for Disease Control and Prevention. August 13, 2024.
Accessed July 7, 2025. https://www.cdc.gov/flu/about/index.html
Ao T, Kikuta J, Ishii M. The effects of vitamin d on immune system and inflammatory diseases. Biomolecules. 2021;11(11):1624. https://pmc.ncbi.nlm.nih.gov/articles/
PMC8615708
Davis RE, Rossier CE, Enfield KB. The impact of weather on influenza and pneumonia mortality in New York City, 1975–2002: a retrospective study. Viboud C, ed. PLoS ONE. 2012;7(3):e34091.
Influenza (seasonal). February 28, 2025. The World Health Organization. Accessed July 7, 2025. https://www.who.int/news-room/fact-sheets/detail/influenza-%28seasonal%29 Key Facts About Seasonal Flu Vaccine. The Centers for Disease Control and Prevention. September 17, 2024. Accessed July 7, 2025. https://www.cdc.gov/flu/vaccines/
keyfacts.html
Selecting Viruses for the Seasonal Influenza Vaccine. The Centers for Disease Control and Prevention. March 12, 2024. Accessed July 7, 2025. https://www.cdc.gov/flu/
vaccine-process/vaccine-selection.html
Treating Flu with Antiviral Drugs. The Centers for Disease Control and Prevention. September 11, 2024. Accessed July 23, 2025. https://www.cdc.gov/flu/treatment/
antiviral-drugs.html