A newer way to manage migraine is here.

There are recent developments in better understanding a potential root cause of migraine pain.

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Explore a Pfizer migraine treatment option

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Explore a Pfizer migraine treatment option

Today’s migraine science

A potential root cause of migraine

There are likely several factors that cause migraine. Many scientists believe a potential root cause is related to a protein called calcitonin gene-related peptide (CGRP). When the brain releases CGRPs, they attach to the receptors, causing nerve inflammation and increased pain signals to the brain.

CGRP is released during migraine attacks

Graphic depicting a normal amount of calcitonin generelated peptide (CGRP) when not experiencing a migraine

Normal

Graphic depicting an increased amount of calcitonin gene-related peptide (CGRP) released during a migraine

During Migraine

How CGRP
antagonists work

CGRP antagonists are one type of medication designed to treat migraine. They target and block pain signals thought to be linked to CGRP activity.

Are you looking for another way to treat your migraine?
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Make sure you get the most out of your doctor visit.

Consider these migraine topics before you go.

Satisfaction

How happy are you with your current treatment?

Frequency

How many days per month do you experience migraine attacks?

Severity

How bad is it and how long do the migraine attacks typically last?

Patterns

Have your migraine attacks changed at all over the past 3-6 months?

Symptoms

Do you ever have symptoms before a migraine attack? What are they like during an attack?

Triggers

What sort of triggers (e.g. food, stress, hormones/menstruation, light, high altitude, lack of sleep, weather changes, etc.) seem to bring on your attacks?

Previous Treatments

What types of medications have you taken for migraine in the past (over-the-counter or prescription)?

Family History

Does anyone in your family experience migraine attacks?

Save on your prescribed Pfizer medications, and get support when you need it.

From co-pay savings cards to financial assistance programs, we have options that can help. Our dedicated customer support team can also help you navigate your insurance benefits, understand your options, and more.

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Getting certain migraine medications may require additional steps.

For some medications, your doctor may need to get approval from your insurance provider before they agree to cover the cost. This is known as a “prior authorization.” Your doctor helps coordinate this process.

If you are prescribed a Pfizer migraine medication, we can help you understand what to do next.

Call our specialist team now:
1-866-222-4183
Monday-Friday 8:00AM – 8:00PM ET

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Frequently asked questions

Are there any recent developments that can help treat migraine?
Yes. Over the last few years, there have been many developments in better understanding the root cause of migraine pain and the introduction of a new class of treatment. If your current migraine medication is not working for you, talk to your doctor about different treatments available today.
What is a migraine?

Migraine is a neurological condition that can cause intense pain on one or both sides of the head for 4 to 72 hours. It is a recurring type of headache. But unlike other headaches, the pain often includes:

  • Throbbing or pulsing
  • Pain in the temples or behind one eye or ear
  • Light and sound sensitivity

There are two common types of migraine: with aura and without aura. Aura is a phase of a migraine attack when people may see flashes of light, have blind spots, or feel tingling in their hands or face.

What does a migraine feel like?

Symptoms can vary but the most common symptoms of migraine include:

  • Throbbing or pulsating pain (typically on one side of the head, but can be on both, front or back, around the eyes, or cheeks)
  • Head pain that gets worse with movement
  • Nausea and/or vomiting
  • Sensitivity to light, sound, and/or smells
What causes a migraine?
The exact cause of migraine is still unknown, but medical experts believe it is caused by abnormal activity in the brain involving nerve pathways and certain chemicals. In addition, many researchers believe that a possible cause of migraine pain is related to a protein called calcitonin gene-related peptide (CGRP). When the brain releases CGRPs, they attach to receptors and cause nerve inflammation—starting a migraine attack.
What are common triggers for migraine?

Many things can trigger a migraine attack, but they’re not the same for everyone.

Common triggers include:

  • Stress
  • Certain foods
  • Alcohol
  • Skipping meals
  • Sudden changes in weather/barometric pressure
  • Hormonal changes in women during their period
  • Changes in sleep patterns

Beyond these triggers, having a family history of migraine and being female can also impact the likelihood of having migraine attacks.

How to get rid of a migraine?

Since the severity and frequency of migraine attacks can differ from person to person, the way they’re treated can vary. There are two main approaches to migraine care: stop migraine attacks after they start (acute) or prevent them before they start (preventive). Many people with migraine use both acute and preventive treatments. These types of treatments can come in the form of oral medications, nasal sprays, injections, or devices.

The good news? There are additional migraine medications that are now available that may bring hope to migraine sufferers.

Are there ways to help treat migraine pain at home?
Yes. You can help manage symptoms at home by napping in a dark room, using an ice pack on the forehead, and staying hydrated. Taking over-the-counter pain relievers may also help if migraine symptoms are mild, but you should talk to your doctor to see if this is right for you.
How long does a migraine last?
An untreated migraine attack can last anywhere from 4 to up to 72 hours.